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KMID : 0387820130200020121
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Clinical Pediatric Hematology-Oncology
2013 Volume.20 No. 2 p.121 ~ p.125
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Early-onset Pericardial Effusion after Autologous Hematopoietic Stem Cell Transplantation in a Child with Neuroblastoma
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Yoon Jong-Hyung
Kim Hak-Jin
Kim Su-Jin
Yun Yong-Soo
Chun Jong-In
Park Hyeon-Jin
Park Byung-Kiu
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Abstract
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Pericardial effusion (PcE) is one of the uncommon complications after hematopoietic stem cell transplantation (HSCT). Although many causes are related with PcE after HSCT, PcE after HSCT is usually late-onset and can be presented as a sign of acute or chronic graft-versus-host disease in allogeneic transplantation. Previous reports of PcE after autol-ogous HSCT are very uncommon. Transplantation-associated thrombotic microangiopathy (TA-TMA) is a kind of renal microvascular complications after HSCT, which is similar to thrombotic thrombocytopenic purpura. The authors report a case of early-onset PcE, which maybe resulted from TA-TMA, after high-dose chemotherapy and autologous pe-ripheral blood HSCT in a 4-year-old child with neuroblastoma.
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KEYWORD
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Pericardial effusion, Autologous hematopoietic stem cell transplantation, Transplantation-associated thrombotic microangiopathy
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